The first drawback I see about nano: what's the incentive for running a full node? You don't get any coins or tx fees AFAIK.
Another point is scalability and TPS: I've heard that's difficult to measure it on NANO, maybe because much PoW are required for high TPS?
Glad to see NANO topic on memo. NANO is my second coin after BCH. Good team and nice community, although a little naive. They don't realize how difficult adoption will be. 0 fees is not enough.
NANO now available on Kraken.